Defined by a very short 4th finger, swollen third finger in adult males, extensive webbing around the feet, and a lack of palatine bones. Found throughout South America and in the Lesser Antilles.

This genus is defined by the presence of a median lingual process. Other characteristics include cryptic coloration, webbed feet, finger I shorter than finger II, and lack of toxins. Distributed from the Pacific coast of Colombia to the Venezuelan tepuis.

The two species of this genus possess cryptic coloration and extensively webbed feet. It can be distinguished from Aromobates and Mannophryne by the absence of dorsolateral stripes and a dark throat patch, respectively. These frogs are distributed throughout the Cordillera Oriental of Colombia.

Distinguished by DNA sequences from other poison frog genera. Morphologically, these frogs possess a pale dorsolateral stripe and webbed feet. They are distributed throughout the Merida Andes of Venezuela and parts of Colombia.

Defined by its dermal collar and stippled abdominal coloration on adult males.